Tetrapyrroles and derivatives
Abcam Nocodazole, Microtubule inhibitor, 10MG
MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clozapine N-o x ide, Metabolite of Clozapine, 100MG
MW 342.8 Da, Purity >99%. Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 168077 maleate, D4 agonist, 50MG
MW 450.49 g/mol, Purity >98%. Potent, selective D₄ dopamine receptor agonist. Displays >400-fold selectivity over D₂ and >300-fold selectivity over D₃ subtypes (Ki values are 11.9, 2540, and 1050 nM for D₄, D₃, and D₂ receptors, respectively). Reverses object recognition deficits.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 168077 maleate, D4 agonist, 10MG
MW 450.49 g/mol, Purity >98%. Potent, selective D₄ dopamine receptor agonist. Displays >400-fold selectivity over D₂ and >300-fold selectivity over D₃ subtypes (Ki values are 11.9, 2540, and 1050 nM for D₄, D₃, and D₂ receptors, respectively). Reverses object recognition deficits.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nafadotride, D3 antagonist, 50MG
MW 365.5 Da, Purity >99%. Potent, selective D3 antagonist (Ki values are 0.52 nM (D3), 269 nM (D4) and 5 nM (D2)).
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Biotin-vitamin B12 | 98.4% | 1581.66 | C73H102CoN16O16PS | 10 MG
Biotin-Vitamin B12 is a biotinylated form of cyanocobalamin (vitamin B12) used as a biochemical reagent and affinity probe. The biotin tag enables capture or detection with streptavidin/avidin systems. Supplied as a solid with high purity, it is formulated for in vitro use and can be prepared for in vivo dosing following manufacturer guidance.
Abcam PD 168568 dihydrochloride, D4 antagonist, 50MG
MW 422.4 g/mol, Purity >99%. Potent and selective D₄ antagonist (Ki = 8.8 nM at D₄, and 1842 nM at D₂). Inhibits amphetamine stimulated locomotor activity in vivo; orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-cis-Diltiazem, cyclic nucleotide-gated channel blocker, 5MG
MW 451 Da, Purity >97%. Selective inhibitor of cyclic nucleotide-gated (CNG) channels. Blocks rod-type CNGA1, olfactory-type CNGA2 and cone-type CNGA3, at micromolar concentrations. Optical isomer of diltiazem (ab120260). Protects against myocardial dysfunction in vitro.
The product is subject to the following: Abcam Restricted Use Statement
![eMolecules AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466756.JPG-250.jpg)
eMolecules AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO
AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO
Abcam LY 294002, PI3-kinase inhibitor, 25MG
MW 307.3 Da, Purity >99%. A highly selective inhibitor of phosphatidylinositol 3-kinase (IC₅₀ = 1.4 μM). Selective over a range of other kinases including protein kinase C, protein kinase A, MAPK and PI4- kinase (IC₅₀ > 50 μM).
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Methylcobalamin 13422-55-4 500mg
Methylcobalamin (CAS 13422-55-4) is a biologically active form of vitamin B12 featuring a methyl group as the ligand to the cobalt ion within the cobalamin structure Functioning as a coenzyme for methionine synthase it facilitates the remethylation of homocysteine to methionine an essential step in methylation metabolism and nucleic acid synthesis Due to its direct involvement in methyl group transfers methylcobalamin is widely utilized in biomedical research to investigate cellular methylation processes nervous system function and disorders related to vitamin B12 deficiency
