Tetrapyrroles and derivatives
Abcam CK 666, Actin polymerization inhibitor, 50MG
MW 296.3 Da, Purity >99%. Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC₅₀ = 17 μM), SpArp2/3 (IC₅₀ = 5 μM) and HsArp2/3 complexes (IC₅₀= 4 μM) by preventing a shift into an active conformation.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Coproporphyrin III dihydrochloride | 68938-73-8 | MFCD00058927 | 99.6% | 727.63 | C36H40Cl2N4O8 | 5 MG
Coproporphyrin III dihydrochloride is a research-grade porphyrin derivative supplied as a purple to purplish red solid powder for in vitro microbiology and biochemical studies, including investigations of bacterial aggregation and biofilm formation.
- High purity (99.57%) suitable for research applications.
- Purple to purplish red solid physical form.
- Available in small quantities including 1 mg, 5 mg, and 10 mg vials.
- Storage: sealed at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
- CAS number 68938-73-8 for unambiguous identification.
- For research use only; not for sale to patients.
Abcam Flupirtine maleate, Neuronal potassium channel opener, 25MG
MW 420.4 Da, Purity >99%. Neuronal potassium channel opener. Activates Kv7.2 channels and potently activates the inwardly rectifying potassium current (KIR; EC₅₀ = 600 nM). Centrally acting, non-opiate analgesic. Neuroprotective and antiapoptotic agent. Also has muscle relaxant properties. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Flupirtine maleate, Neuronal potassium channel opener, 10MG
MW 420.4 Da, Purity >99%. Neuronal potassium channel opener. Activates Kv7.2 channels and potently activates the inwardly rectifying potassium current (KIR; EC₅₀ = 600 nM). Centrally acting, non-opiate analgesic. Neuroprotective and antiapoptotic agent. Also has muscle relaxant properties. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Verteporfin (Visudyne), Benzoporphyrin derivative, 25MG
MW 718.8 Da, Purity >96%. Benzoporphyrin derivative. Antiangiogenic agent. Produces ROS on stimulation with nonthermal red light in the presence of oxygen. Prevents corneal neovascularization and shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam P5091, USP-7 inhibitor, 25MG
MW 348.2 Da, Purity >98%. Potent, selective and cell-permeable USP-7 inhibitor (EC₅₀ = 4.2 μM). Induces apoptosis in cancer cells in vitro. Antiangiogenic and antitumor agent. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Coproporphyrin III dihydrochloride | 68938-73-8 | MFCD00058927 | 99.6% | 727.63 | C36H40Cl2N4O8 | 1 MG
Coproporphyrin III dihydrochloride is a porphyrin derivative provided as a high-purity research reagent for biochemical and analytical applications. It is supplied in both solid and solution formats to support assays, reference standards, and method development.
- High purity: 99.6% suitable for analytical and research use.
- Available in solid and solution formats for experimental flexibility.
- Multiple pack sizes: includes 1 mg, 5 mg, and 10 mg options; larger quantities by request.
- Well-characterized: CAS 68938-73-8, molecular weight 727.63, and defined chemical formula.
- Applicable for biochemical assays, analytical characterization, and reagent preparation.
Frontier Specialty Chemicals 100MG COPROPORPHYRIN III TETRA
Coproporphyrin III tetramethyl ester; CAS: 5522-63-4; 100mg
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00151109 | 98.0% | 100 MG
Protoporphyrin IX is an endogenous metabolite and a final intermediate in the heme biosynthetic pathway. It functions as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also acts as a photosensitizer that undergoes photobleaching from light irradiation. It accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA).
- Endogenous metabolite and final intermediate in heme biosynthetic pathway
- Functions as a radiation sensitizer
- Enhances ROS generation even in hypoxic conditions
- Induces DNA damage
- Acts as a photosensitizer that undergoes photobleaching from light irradiation
- Accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA)
- Shows promise as a sonodynamic and photodynamic agent for various cancers, such as bladder cancer and nodular basal cell carcinoma
Abcam Amylin (human), Endogenous peptide, 500UG
MW 3903.3 Da, Purity >95%. Amylin (human), Endogenous peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Hematoporphyrin monomethyl ether | 148471-91-4 | MFCD32215011 | 95.0% | C70H80N8O12 | 10MG
Hematoporphyrin monomethyl ether is a porphyrin-related photosensitizer used as a research reagent for photodynamic studies. It produces singlet oxygen when activated by light and is commonly applied in photodynamic therapy research, cellular photochemistry, and light-activated imaging experiments.
- Porphyrin-derived photosensitizer with high singlet oxygen yield.
- Suitable for photodynamic therapy research and in vitro photochemistry.
- Solid with a purple to purplish red appearance for easy visual identification.
- Available in small research pack sizes suitable for laboratory experiments.
- Store protected from light and refrigerate to maintain stability.
Abcam Bisindolylmaleimide II, PKC inhibitor, 5MG
MW 438.5 Da, Purity >97%. Potent, selective ATP-competitive PKC inhibitor (IC₅₀ values are 0.01, 0.75 and 2 μM for PKC, phosphorylase kinase and PKA respectively). Potent noncompetitive nAChR antagonist (IC₅₀ = 0.03 μM, catecholamine secretion in nicotine-stimulated PC-12 cells). Shows more potent antinicotinic effects than Bisindolylmaleimide IV (ab144208) and V (ab144205). Induces apoptosis and shows antiproliferative effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BIM 23056, Somatostatin receptor 5 (sst5) antagonist, 1MG
MW 1232.5 Da. BIM 23056, Somatostatin receptor 5 (sst5) antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Chem-Impex International, Inc. Hemin (from porcine) | 16009-13-5 | MFCD00010726 | 1G
Hemin (from porcine), 16009-13-5, MFCD00010726, 1G